Gel Permeation Chromatography (GPC) is a technique which separates components of a sample based on their molecular size. Since lipids are very large molecules compared to the target compounds in these methods, they are effectively removed from the extract prior to analysis. This improves method performance and extends GC column life, leading to more efficient analyses. With auto sampling and automatic fraction collection as part of the GPC system, the cleanups can be performed with little or no operator intervention, requiring only that the final extracts be concentrated down.

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