Pharmaceutical
Exova assisting the pharmaceutical sector
Pharmaceutical development has become a global business dominated by a small number of large R&D based ‘blue chip’ companies. The last 20-25 years has seen the emergence of a number of ‘high tech/biotech’ companies who are exploring new technologies for the development and targeting of drugs.
With many well known drugs coming out of patent protection, the generic market continues to grow with the significant influence of India and Asia in manufacturing.
Exova assists all three sectors of the market whether for QC batch release of raw materials and generics, development of formulations for new drugs or supporting the ‘blue chip’ pharmaceutical companies in their R&D, stability storage or calibration of their instruments.
The medical devices market is also a growing area for testing development. Whether this is the non destructive testing (NDT) of artificial joint implants or the testing of polymer for drug delivery, Exova has unrivalled experience.
Giving clients confidence in their products
A client of Exova’s pharmaceutical testing and advisory centre in Camberly, Surrey required an Intravenous (IV) formulation of their Active Pharmaceutical Ingredient (API), which lacked stability. At low pH there was greater stability, but insufficient solubility to accommodate the high dose.
A shelf-life of at least 6 months was required for the drug product and on dilution, there had to be sufficient stability at room temperature to support a 12-hour shelf-life for infusion.
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